Revolution Main Uses
Broad-Spectrum Parasite Prevention: A monthly topical solution used to protect young pets from multiple internal and external parasites simultaneously.
Flea Control: Kills adult fleas (Ctenocephalides felis) and prevents flea eggs from hatching for one full month.
Heartworm Prevention: Prevents heartworm disease caused by Dirofilaria immitis.
Ear Mite Treatment: Effectively treats and controls ear mite (Otodectes cynotis) infestations.
Intestinal Worms (Cats): Treats and controls roundworms (Toxocara cati) and hookworms (Ancylostoma tubaeforme) in kittens.
Mange & Ticks (Dogs): Specifically in puppies, it treats sarcoptic mange and aids in the control of American dog ticks (Dermacentor variabilis).
 
Revolution Active Ingredients
Selamectin (60 mg/mL): A semi-synthetic compound of the avermectin class. The 0.25 mL tube for puppies/kittens contains 15 mg of selamectin.
Mechanism of Action: Selamectin is absorbed through the skin into the bloodstream and then redistributed back to the skin and intestinal tract. It works by interfering with the chloride channel neurotransmission in parasites, leading to neuromuscular paralysis and death.
Systemic Distribution: It provides protection both externally (on the skin) and internally (within the blood and gut).
 
Revolution Dosage & Administration
Recommended Dosage: The standard minimum dose is 6 mg/kg (2.7 mg/lb) of body weight.
Target Weight: For puppies and kittens weighing up to 2.5 kg (5 lbs).
Administration:
Press the cap down to puncture the seal, then remove the cap.
Part the hair at the base of the neck (in front of the shoulder blades) until skin is visible.
Squeeze the entire contents of the 15 mg tube directly onto the skin in one spot.
Timing: Apply once every 30 days. It is quick-drying and generally waterproof after 2 hours.
Age Requirements: Safe for use at 6 weeks of age and older.
 
Revolution Side Effects & Safety
Common Side Effects: Temporary hair loss, stiff hair, or a slight powdery residue at the application site.
Rare Side Effects: Digestive upset (vomiting, diarrhea), decreased appetite, lethargy, or salivation.
Safety Warnings:
Do not use on sick, debilitated, or severely underweight animals.
Species Safety: Ensure you use the correct tube size for the pet's weight; do not use dog-specific larger tubes on cats.
Heartworm Testing: In Canada, it is recommended that dogs over 6 months of age be tested for existing heartworm infection before starting Revolution.
Safe for Breeding: Tested and confirmed safe for use in breeding, pregnant, and lactating dogs and cats.
 
Revolution Manufacturer Information
Manufacturer: Zoetis Canada.
Official Website: https://www.zoetis.ca
Brand Introduction: Zoetis is the leading global animal health company. Revolution has been a cornerstone of veterinary parasite prevention in Canada for over 20 years, valued for its high safety profile in very young animals and its "all-in-one" topical convenience.