Revolution® Plus (selamectin 60 mg/mL and sarolaner 10 mg/mL) is available as a colorless to yellow, ready to use solution in single dose tubes for topical (dermal) treatment. The content of each tube is formulated to provide a minimum of 6 mg/kg (2.7 mg/lb) of body weight of selamectin and 1 mg/kg (0.45 mg/lb) of body weight of sarolaner. Revolution® Plus is recommended for use in cats and kittens 8 weeks of age and older, and weighing 1.3 kg or greater, for the following indications:
 
Revolution® Plus kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations for 5 weeks (35 days),
For the treatment and control of tick infestations with Ixodes scapularis (black-legged tick) and Dermacentor variabilis (American dog tick) for 5 weeks (35 days) and with Amblyomma maculatum (Gulf Coast tick) for 4 weeks (28 days),
For the prevention of heartworm disease caused by Dirofilaria immitis,
For the treatment and control of ear mite (Otodectes cynotis) infestations, and
For the treatment and control of roundworm (Toxocara cati) and intestinal hookworm (Ancylostoma tubaeforme) infections.