Onsior Tablets Main Uses
Osteoarthritis Management: Indicated for the treatment of pain and inflammation associated with chronic osteoarthritis in dogs.
Soft Tissue Surgery: Used for the treatment of post-operative pain and inflammation associated with soft tissue surgeries.
 
Onsior Tablets Active Ingredients
Robenacoxib: A non-narcotic, non-steroidal anti-inflammatory drug (NSAID) belonging to the coxib class.
Mechanism of Action:
COX-2 Selectivity: Specifically inhibits the cyclooxygenase-2 (COX-2) enzyme, which is responsible for producing the prostaglandins that cause pain and inflammation.
COX-1 Sparing: At recommended doses, it has minimal effect on the COX-1 enzyme, which protects the gastrointestinal lining and maintains normal kidney blood flow.
Formulation: Flavored, non-scored tablets designed for high palatability and voluntary acceptance by most dogs.
 
Onsior Tablets Dosage & Administration
Osteoarthritis Dosage: The recommended dose is 1 mg/kg (range 1–2 mg/kg) administered once daily at the same time each day.
Soft Tissue Surgery Dosage: The recommended dose is 2 mg/kg (range 2–4 mg/kg) administered as a single dose prior to surgery. For post-operative care, once-daily treatment may continue for up to two additional days.
Weight Constraints: Safe for dogs weighing at least 2.5 kg (5.5 lbs) and at least 4 months of age (soft tissue surgery) or 6 months of age (chronic osteoarthritis).
Administration:
Tablets should not be broken or divided.
For maximum efficacy, administer without food or with a small quantity of food.
 
Onsior Tablets Side Effects & Safety
Common Side Effects: Generally well tolerated; however, mild gastrointestinal signs such as vomiting, soft stools, or diarrhea may occur.
Safety Warnings:
Contraindications: Do not use in dogs with gastrointestinal ulcers, severe liver disease, or known hypersensitivity to robenacoxib.
Drug Interactions: Do not administer concurrently with other NSAIDs (e.g., Metacam, Rimadyl) or corticosteroids (e.g., Prednisone).
Monitoring: For long-term osteoarthritis therapy, veterinarians recommend monitoring liver enzymes at the start of treatment (weeks 2, 4, and 8) and every 3–6 months thereafter.
Discontinuation: Stop use immediately and contact a veterinarian if the dog develops anorexia (loss of appetite), lethargy, or repeated vomiting.
Duration of Use: While surgery protocols are limited to 3 days, use for osteoarthritis can be long-term under strict veterinary supervision and regular blood monitoring.
 
Onsior Tablets Manufacturer Information
Manufacturer: Elanco Canada Limited.
Official Website: https://www.elanco.ca/
Brand Introduction: Elanco is a global leader in animal health with Canadian headquarters in Mississauga, Ontario. They specialize in innovative products that improve the health of pets and livestock. Onsior is a cornerstone of their pain management portfolio, known for its "Targeted and Tough" approach to inflammation while maintaining a favorable safety profile for canine patients.