Deramaxx Main Uses
Relief of pain and inflammation associated with orthopedic surgery in dogs.
Management of chronic pain and lameness associated with osteoarthritis in dogs.
Relief of postoperative pain and inflammation associated with dental surgery in dogs.
 
Deramaxx Active Ingredients
Deracoxib: Deracoxib is a selective COX-2 inhibitor; it preferentially inhibits cyclooxygenase-2 (COX-2), the enzyme responsible for prostaglandin synthesis in inflamed tissues, while sparing COX-1 at therapeutic doses.
Mechanism of Action: Deracoxib inhibits COX-2-mediated prostaglandin E2 production, reducing the chemical signals that produce pain, swelling, and inflammation at the site of injury or joint disease. By selectively targeting COX-2, Deramaxx reduces the gastrointestinal side effects more commonly seen with non-selective NSAIDs, though GI and renal monitoring remains important during long-term use.
 
Deramaxx Dosage & Administration
Administer exactly as prescribed by your veterinarian.
Available in 25 mg, 75 mg, and 100 mg chewable tablets; your veterinarian will select the appropriate strength based on your dog's weight and indication.
Administer with food to this reduces the risk of gastrointestinal upset.
If a dose is missed, give it at the next scheduled time. Do not administer two doses at once.
A valid veterinary prescription is required before dispensing.
 
Deramaxx Safety & Side Effects
Adverse reactions may include vomiting, diarrhea, decreased appetite, dark or tarry stools, increased water consumption, increased urination, lethargy, and, in rare cases, seizures or jaundice.
Do not administer to cats. Deramaxx is for dogs only.
Do not use concurrently with other NSAIDs, corticosteroids, or aspirin without veterinary guidance, as this significantly increases the risk of serious adverse effects.
Use with caution in dogs with liver, kidney, cardiovascular, or gastrointestinal disease.
Dogs receiving long-term NSAID therapy may benefit from periodic veterinary monitoring, including assessment of liver and kidney function.
Use with caution in dogs that are dehydrated, receiving diuretic therapy, or have conditions that may affect kidney function.
Discontinue use and contact your veterinarian if adverse effects occur.
 
Deramaxx Manufacturer Information
Supplier: Elanco Canada Limited
Official Website: https://www.elanco.com/en-ca
Brand Introduction: Elanco is one of the world's leading animal health companies, operating in Canada through Elanco Canada Limited in Mississauga, Ontario. Deramaxx (deracoxib) is a Health Canada-approved prescription veterinary drug for pain management in dogs.