Cerenia Main Uses
Prevention and treatment of acute vomiting caused by various conditions (e.g., gastroenteritis, dietary indiscretion, some infections like parvovirus, or pancreatitis).
Prevention of vomiting associated with motion sickness.
 
Cerenia Active Ingredients
Maropitant Citrate: It functions as a potent and selective neurokinin-1 receptor antagonist.
How the product works:
Vomiting is triggered by the binding of a key neurotransmitter called Substance P to neurokinin-1 receptors in the "vomiting center" (emetic center) of the brain.
Maropitant works by blocking these neurokinin-1 receptors in the central nervous system (CNS).
By blocking this crucial signal, maropitant stops both peripheral (from the gut/body) and central (from the brain/vestibular system, as in motion sickness) stimuli from triggering the vomiting reflex, providing broad and effective antiemetic action.
 
Cerenia Dosage & Administration
Treatment of Acute Vomiting: A minimum of 2 mg/kg body weight orally once daily.
Prevention of Vomiting due to Motion Sickness: A minimum of 8mg/kg body weight orally once daily.
Administration timing
Acute Vomiting: Typically administered once daily. May be given with or without food.
Motion Sickness: Administer a minimum of two hours prior to travel and dogs should be fed 1 hours before treatment with Cerenia tablets to mitigate side effect of vomiting
Age:
Acute Vomiting: For dogs >10 weeks old
Motion Sickness: For dogs > 4 months old.
Weight: The dose must be calculated precisely based on the dog's body weight to ensure efficacy and safety.
 
Cerenia Side Effects & Safety
Common or rare side effects:
Common (especially at the higher motion sickness dose): Vomiting/retching, hypersalivation (excessive drooling), lethargy, depression
Less Common: Diarrhea, anorexia (decreased appetite), trembling/muscle tremors, ataxia (uncoordinated walking).
Safety warnings and contraindications:
Cerenia is contraindicated in dogs suspected of having a gastrointestinal obstruction (blockage) or toxin ingestion. The underlying cause of vomiting must be addressed first.
Use with caution in dogs with heart disease or hepatic dysfunction.
Recommended safe duration of use:
Acute Vomiting: Up to 5 consecutive days for young dogs (2-7 months of age). For dogs >7 months old, it may be administered once daily until resolution, but a veterinarian should re-evaluate the patient if vomiting persists.
Motion Sickness: Up to 2 consecutive days.
 
Cerenia Manufacturer Information
Manufacturer: Zoetis Canada Inc. (Canadian subsidiary of Zoetis).
Official Website: https://www2.zoetis.ca/
Brand introduction: Cerenia is a prescription-only veterinary drug developed by Zoetis, a global animal health company. It is a leading and highly effective antiemetic medication widely used by Canadian veterinarians for both the treatment and prevention of acute vomiting and motion sickness in dogs.