Otizole Main Uses
Indicated for treating otitic and dermal infections caused by pathogens sensitive to miconazole nitrate or polymyxin B sulfate, along with associated inflammation
Common clinical uses include otitis externa in dogs, ear mite (Otodectes cynotis)– associated otitis in cats, allergic dermatitis in dogs, fungal infections caused by Microsporum canis, bacterial dermatitis, and non‑specific dermatitis in dogs and cats.
 
Otizole Active Ingredients
Miconazole nitrate (23 mg/mL): Antifungal agent that eliminates fungal organisms such as yeast and molds in the ears and on skin
Polymyxin B sulfate (0.5293 mg/mL): Antibacterial agent that targets bacteria responsible for ear and skin infections
Prednisolone acetate (5 mg/mL): Corticosteroid that reduces inflammation and itching associated with infections
 
Otizole Dosage & Administration
Available in 15 mL, 30 mL, and 100 mL formats
Administration guidance: Shake well; clean the ear canal before instillation for otitis externa; apply per veterinarian’s instructions to affected ear(s) or skin.
 
Otizole Side Effects & Safety
This is a prescription-only medication requiring veterinary oversight
Should be stored at 15-30°C, protected from freezing and light
Contains a corticosteroid (prednisolone acetate), which may have contraindications for certain health conditions requiring veterinary evaluation
 
Otizole Manufacturer Information
Manufacturer: Can-Vet Animal Health Supplies Ltd.
Official Website: https://www.canvetah.ca/
Brand Introduction: Can-Vet Animal Health Supplies Ltd. is a Canadian veterinary pharmaceutical company based in Guelph, Ontario, that manufactures veterinary medications approved by Health Canada.
 
Reference:
https://pdf.hres.ca/dpd_pm/00056902.PDF